David Anthony Rusling Portrait

Dr David Rusling

Senior Lecturer

David.Rusling@port.ac.uk

PhD Supervisor

View my research outputs
Faculty of Science and Health School of Medicine, Pharmacy and Biomedical Sciences Pharmacy, pharmacology, and biomedical sciences Biological sciences Frontier Biomolecular Science Institute of Life Sciences and Healthcare

Summary

**Accepting self-funded PhD students** 

Dr David Rusling is a Senior Lecturer in Pharmacology within the School of Pharmacy and Biomedical Sciences at the 91¸£ÀûÍø. His research focuses on the self-assembly and recognition of nucleic acid sequences from a biological, therapeutic and nanotech perspective. One of his long-term research projects is seeking to improve the triplex-forming properties of oligonucleotides, a class of DNA-binding agent capable of recognising unique base sequences within the major groove of double-helical DNA. Such molecules have potential to modulate the expression of specific genes, as well as introduce functionality into artificial DNA structures assembled for DNA nanotechnology. David’s recent research has appeared in several prominent journals, including Nucleic Acids Research, ACS Nano, Angewandte Chemie, and Chemical Communications.

Research outputs

2024

Kalra, S., Donnelly, A., Singh, N., Matthews, D., Del Villar-Guerra, R., Bemmer, V., Dominguez, C., Allcock, N., Cherny, D., Revyakin, A., Rusling, D. A.

15 May 2024, In: Journal of the American Chemical Society. 146, 19, p. 13617–13628, 12p.

Research output: Article

2023

Zhao, Y., Chandrasekaran, A. R., Rusling, D. A., Woloszyn, K., Hao, Y., Hernandez, C., Vecchioni, S., Ohayon, Y. P., Mao, C., Seeman, N. C., Sha, R.

2 Feb 2023, In: Journal of the American Chemical Society. 145, 6, p. 3599–3605

Research output: Article

Zou, J., Stammers, A. C., Taladriz-Sender, A., Withers, J. M., Christie, I., Santana Vega, M., Aekbote, B. L., Peveler, W. J., Rusling, D. A., Burley, G. A., Clark, A. W.

10 Jan 2023, In: ACS Nano. 17, 1, p. 752-759, 8p.

Research output: Article

2021

Rusling, D. A.

21 Jul 2021, In: Nucleic Acids Research. 49, 13, p. 7256-7266

Research output: Article

2020

Sayoh, I., Rusling, D. A., Brown, T., Fox, K. R.

28 Jan 2020, In: ACS Omega. 5, 3, p. 1679-1687, 9p.

Research output: Article

Carter, M. L. J., Rusling, D. A., Gurr, S., Brown, T., Fox, K. R.

1 Jan 2020, In: Biophysical Chemistry. 256, 5p., 106270

Research output: Article